AI tools on the Mac range from chat clients for cloud models to apps that run language models locally on Apple silicon. Desktop clients like Cherry Studio and Chatbox connect to several providers using your own API keys, while Jan can run open-weight models offline so prompts stay on your machine.
First decide between local and cloud inference: local models need plenty of unified memory, while cloud clients bill through each provider's API pricing. Most apps listed are open source and many are cross-platform rather than native. Newer entries focus on coding agents, such as CodexBar, which shows usage stats for OpenAI Codex and Claude Code. The field moves fast, so check recent activity.